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Rejuran, Bio Stimulator and Bio Modulator for Skin Rejuvenation
Rejuran - Regenerative skin therapy
At Epicell, we focus on treatments that go beyond surface-level change—targeting the skin’s ability to repair, regenerate, and perform over time.
Rejuran is a leading bio-stimulatory treatment that works at a cellular level to restore skin integrity, improve collagen production, and strengthen the skin barrier. Using polynucleotides (PN), it supports true skin regeneration—making it ideal for patients seeking long-term skin health, not just temporary results.
More Than One Approach to Bio-Stimulation
While Rejuran is a cornerstone treatment, true skin regeneration is often achieved through a layered, multimodal approach.
At Epicell, we utilise a range of advanced treatments that also stimulate the skin in different ways:
Collagen Stimulation (Mechanical)
Treatments such as skin needling create controlled micro-injury to trigger collagen and elastin production—improving texture, scarring, and overall skin strength.
Thermal Stimulation (Laser-Based)
Technologies like Laser Genesis gently heat the dermis, stimulating collagen while reducing inflammation and vascular reactivity.
Cellular Repair (LED Therapy)
Healite II enhances cellular activity, accelerates healing, and supports optimal skin recovery—essential for maintaining results.
Chemical Stimulation (Clinical Peels)
Advanced skin peels encourage cell turnover, regulate oil flow, and improve skin clarity—supporting the regenerative process.
Each modality works differently, and when combined strategically, they create a synergistic effect—enhancing outcomes while maintaining skin integrity.
Rejuran for Under Eyes
The under-eye area requires a refined and thoughtful approach.
Rejuran is uniquely suited to this delicate region, helping to:
Improve thin, crepey skin
Soften fine lines and textural changes
Strengthen and thicken the dermis
Enhance hydration and resilience
Rather than adding volume, it focuses on restoring skin quality, creating a natural, refreshed appearance.
Our Philosophy
At Epicell, we don’t rely on a single treatment.
We design comprehensive skin strategies—combining bio-stimulatory therapies to achieve results that are progressive, natural, and long-lasting.
True skin change is built, not rushed.
Through regenerative treatments like Rejuran and complementary modalities, we help your skin become stronger, healthier, and more resilient over time.
Your First Consultation at Epicell: What to Expect
Walking into a skin or medical aesthetics clinic for the first time can feel a little overwhelming. There are so many treatments available, and it can be difficult to know what your skin actually needs or where to begin. At Epicell Skin Clinic, we believe your first appointment should start with a conversation — not a treatment. Our approach is consultation-led, which means we take the time to understand your concerns, assess what we can see clinically and develop a treatment
Kymberley Dench
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Laser Genesis is a gentle, non-invasive skin treatment that improves tone, texture, and redness with no downtime. This article explains what to expect, key benefits, results over time, and why it’s popular in Melbourne clinics.
Peter Roodnat
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Choosing Between Excel V+ and IPL for Your Skin Concerns
Are you confused about which laser treatment will give you the best results for your skin concerns? You're not alone. At Epicell, we're often asked: "Should I choose Excel V+ or IPL for my pigmentation?" As Melbourne's leading advanced skincare clinic, we've treated thousands of patients with both technologies. Here's your complete guide to making the right choice. What is Excel V+ Laser Treatment? Excel V+ is the latest generation vascular laser that targets various skin iss
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Your First Consultation at Epicell: What to Expect
Walking into a skin or medical aesthetics clinic for the first time can feel a little overwhelming. There are so many treatments available, and it can be difficult to know what your skin actually needs or where to begin. At Epicell Skin Clinic, we believe your first appointment should start with a conversation — not a treatment. Our approach is consultation-led, which means we take the time to understand your concerns, assess what we can see clinically and develop a treatment
Kymberley Dench
3 days ago3 min read
What to Expect from Laser Genesis Treatments: Benefits, Results & Recovery
Laser Genesis is a gentle, non-invasive skin treatment that improves tone, texture, and redness with no downtime. This article explains what to expect, key benefits, results over time, and why it’s popular in Melbourne clinics.
Peter Roodnat
4 days ago3 min read
Choosing Between Excel V+ and IPL for Your Skin Concerns
Are you confused about which laser treatment will give you the best results for your skin concerns? You're not alone. At Epicell, we're often asked: "Should I choose Excel V+ or IPL for my pigmentation?" As Melbourne's leading advanced skincare clinic, we've treated thousands of patients with both technologies. Here's your complete guide to making the right choice. What is Excel V+ Laser Treatment? Excel V+ is the latest generation vascular laser that targets various skin iss
Stiletto Styling
Mar 263 min read
Unlock the Secret to Flawless Skin with Cutera Excel V Plus: The Ultimate Treatment for All Your Skin Concerns!
Are you frustrated with skin imperfections that seem to stick around no matter how many products you try? If you've been on an endless quest for flawless skin, your search may soon be over with the Cutera Excel V Plus. This innovative laser treatment system offers targeted solutions for a variety of skin concerns, including pigmentation issues, vascular lesions, stubborn cherry angiomas, and unwanted leg veins. In this post, we will explore the specific treatments available w
Kymberley Dench
May 29, 20254 min read
Why Do I Look Tired Even When My Skin Looks Good?
Have you ever looked in the mirror and thought, “I look tired”, even when you've had a good night's sleep? You may have healthy skin, a good skincare routine and very few wrinkles, yet still feel that your face — particularly around the eyes — looks tired, heavy or less refreshed than it used to. The reason may not be your skin. As we age, changes occur in the skin, collagen, facial volume and the tissues surrounding the eyes. These changes can alter the way light and shadow
Kymberley Dench
10 hours ago5 min read
How and Why Does Our Face Age? Understanding Facial Ageing
Ageing is something every skin experiences, but facial ageing is much more complex than simply developing wrinkles. As we age, changes occur throughout the skin and the underlying structures of the face. Collagen and elastin gradually change, the skin can become thinner and less resilient, facial volume can shift or decrease, and changes occur within the deeper tissues that support the face. Environmental factors, particularly cumulative UV exposure, can accelerate some of th
Kymberley Dench
23 hours ago4 min read
Why Does Facial Redness Keep Coming Back? Causes, Triggers and Treatment
You may have noticed that your skin looks calmer after treatment, only for the redness to gradually return. This can be frustrating, particularly when you have invested time and money into improving your skin. The reason is that facial redness is often influenced by more than one factor. Some redness is associated with visible blood vessels, while other redness can be related to inflammation, rosacea, acne, sensitivity or environmental triggers. Understanding what is contribu
Kymberley Dench
23 hours ago4 min read
Rosacea or Broken Capillaries? Understanding the Cause of Red Skin
If you have red cheeks, a red nose or small visible blood vessels across your face, you may have wondered whether you have rosacea or simply broken capillaries. The two can look similar, and in some people they can occur together. Understanding the difference can help determine the most appropriate approach to managing your skin. At Epicell Skin Clinic in Pascoe Vale, Melbourne, we assess the skin carefully to determine whether redness appears to be associated with visible bl
Kymberley Dench
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Why Is My Face Always Red? Common Causes of Facial Redness
If your face frequently looks red, flushed or irritated, you may be wondering why it happens and whether it is simply sensitive skin or something that should be assessed. Facial redness is common and can have many different causes. For some people, redness comes and goes. For others, it becomes more persistent and may be associated with visible blood vessels, inflammation, rosacea, acne or sensitivity. At Epicell Skin Clinic in Pascoe Vale, Melbourne, we assess the skin caref
Kymberley Dench
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Why Does Pigmentation Come Back?
You've treated your pigmentation, your skin looks clearer, and then months later you notice those darker patches starting to appear again. Why does pigmentation come back? The answer is that pigmentation is often more than a surface problem. While a treatment may reduce the visible pigment, the factors that caused it can still be present. This is particularly relevant for conditions such as melasma, which can be persistent and prone to recurrence. At Epicell Skin Clinic in Pa
Kymberley Dench
1 day ago5 min read
Post-Inflammatory Pigmentation After Acne: Why It Happens and What Can Help
Your acne has finally settled, but you're still left with brown or darker marks where the breakouts were. If this sounds familiar, you may be experiencing post-inflammatory pigmentation after acne, also known as post-inflammatory hyperpigmentation or PIH. It is a common concern we see in clinic, and one of the most frustrating parts of having acne because the inflammation may have disappeared while the pigmentation remains. At Epicell Skin Clinic in Pascoe Vale, Melbourne, we
Kymberley Dench
1 day ago5 min read
Is It Pigmentation or Melasma? Understanding the Difference
If you have noticed brown or darker patches appearing on your face, you may have wondered: “Is this pigmentation or melasma?” Although the terms are sometimes used interchangeably, they are not the same thing. Pigmentation is a broad term used to describe areas of skin that appear darker than the surrounding skin. Melasma is a specific chronic pigmentary condition that can have different triggers and requires a more considered approach to treatment. At Epicell Skin Clinic in
Kymberley Dench
1 day ago4 min read
Anti Aging at Epicell Cosmetic Medicine Biostimulants Bioremodelling and Skin Health Treatments
Skin ageing is not only about lines. It is also about texture, tone, firmness, hydration, volume changes, and how well the skin repairs itself over time. That is why a modern cosmetic medicine plan should do more than chase a single wrinkle. At Epicell, the focus is on supporting skin health through evidence-informed treatments, careful assessment, and natural-looking results. Biostimulants, bioremodelling treatments, wrinkle-relaxing injections, skin boosters, and device-bas
Kymberley Dench
3 days ago7 min read
The Complete Guide to Broken Capillaries: Causes, Prevention & Effective Treatments
Broken capillaries, ook wel spider veins genoemd, zijn kleine zichtbare bloedvaatjes die vooral voorkomen op wangen, neus en kin. Ze ontstaan door factoren zoals genetische aanleg, zonbeschadiging, temperatuurschommelingen, alcoholgebruik, rosacea en huidveroudering. Hoewel ze onschuldig zijn, verdwijnen ze niet vanzelf en kunnen ze steeds zichtbaarder worden.
Peter Roodnat
3 days ago2 min read
Your First Consultation at Epicell: What to Expect
Walking into a skin or medical aesthetics clinic for the first time can feel a little overwhelming. There are so many treatments available, and it can be difficult to know what your skin actually needs or where to begin. At Epicell Skin Clinic, we believe your first appointment should start with a conversation — not a treatment. Our approach is consultation-led, which means we take the time to understand your concerns, assess what we can see clinically and develop a treatment
Kymberley Dench
3 days ago3 min read
What to Expect from Laser Genesis Treatments: Benefits, Results & Recovery
Laser Genesis is a gentle, non-invasive skin treatment that improves tone, texture, and redness with no downtime. This article explains what to expect, key benefits, results over time, and why it’s popular in Melbourne clinics.
Peter Roodnat
4 days ago3 min read
Choosing Between Excel V+ and IPL for Your Skin Concerns
Are you confused about which laser treatment will give you the best results for your skin concerns? You're not alone. At Epicell, we're often asked: "Should I choose Excel V+ or IPL for my pigmentation?" As Melbourne's leading advanced skincare clinic, we've treated thousands of patients with both technologies. Here's your complete guide to making the right choice. What is Excel V+ Laser Treatment? Excel V+ is the latest generation vascular laser that targets various skin iss
Stiletto Styling
Mar 263 min read
Why Do I Look Tired Even When My Skin Looks Good?
Have you ever looked in the mirror and thought, “I look tired”, even when you've had a good night's sleep? You may have healthy skin, a good skincare routine and very few wrinkles, yet still feel that your face — particularly around the eyes — looks tired, heavy or less refreshed than it used to. The reason may not be your skin. As we age, changes occur in the skin, collagen, facial volume and the tissues surrounding the eyes. These changes can alter the way light and shadow
Kymberley Dench
10 hours ago5 min read
How and Why Does Our Face Age? Understanding Facial Ageing
Ageing is something every skin experiences, but facial ageing is much more complex than simply developing wrinkles. As we age, changes occur throughout the skin and the underlying structures of the face. Collagen and elastin gradually change, the skin can become thinner and less resilient, facial volume can shift or decrease, and changes occur within the deeper tissues that support the face. Environmental factors, particularly cumulative UV exposure, can accelerate some of th
Kymberley Dench
23 hours ago4 min read
Why Does Facial Redness Keep Coming Back? Causes, Triggers and Treatment
You may have noticed that your skin looks calmer after treatment, only for the redness to gradually return. This can be frustrating, particularly when you have invested time and money into improving your skin. The reason is that facial redness is often influenced by more than one factor. Some redness is associated with visible blood vessels, while other redness can be related to inflammation, rosacea, acne, sensitivity or environmental triggers. Understanding what is contribu
Kymberley Dench
23 hours ago4 min read
Rosacea or Broken Capillaries? Understanding the Cause of Red Skin
If you have red cheeks, a red nose or small visible blood vessels across your face, you may have wondered whether you have rosacea or simply broken capillaries. The two can look similar, and in some people they can occur together. Understanding the difference can help determine the most appropriate approach to managing your skin. At Epicell Skin Clinic in Pascoe Vale, Melbourne, we assess the skin carefully to determine whether redness appears to be associated with visible bl
Kymberley Dench
23 hours ago3 min read
Why Is My Face Always Red? Common Causes of Facial Redness
If your face frequently looks red, flushed or irritated, you may be wondering why it happens and whether it is simply sensitive skin or something that should be assessed. Facial redness is common and can have many different causes. For some people, redness comes and goes. For others, it becomes more persistent and may be associated with visible blood vessels, inflammation, rosacea, acne or sensitivity. At Epicell Skin Clinic in Pascoe Vale, Melbourne, we assess the skin caref
Kymberley Dench
23 hours ago4 min read
Why Does Pigmentation Come Back?
You've treated your pigmentation, your skin looks clearer, and then months later you notice those darker patches starting to appear again. Why does pigmentation come back? The answer is that pigmentation is often more than a surface problem. While a treatment may reduce the visible pigment, the factors that caused it can still be present. This is particularly relevant for conditions such as melasma, which can be persistent and prone to recurrence. At Epicell Skin Clinic in Pa
Kymberley Dench
1 day ago5 min read
Post-Inflammatory Pigmentation After Acne: Why It Happens and What Can Help
Your acne has finally settled, but you're still left with brown or darker marks where the breakouts were. If this sounds familiar, you may be experiencing post-inflammatory pigmentation after acne, also known as post-inflammatory hyperpigmentation or PIH. It is a common concern we see in clinic, and one of the most frustrating parts of having acne because the inflammation may have disappeared while the pigmentation remains. At Epicell Skin Clinic in Pascoe Vale, Melbourne, we
Kymberley Dench
1 day ago5 min read
Is It Pigmentation or Melasma? Understanding the Difference
If you have noticed brown or darker patches appearing on your face, you may have wondered: “Is this pigmentation or melasma?” Although the terms are sometimes used interchangeably, they are not the same thing. Pigmentation is a broad term used to describe areas of skin that appear darker than the surrounding skin. Melasma is a specific chronic pigmentary condition that can have different triggers and requires a more considered approach to treatment. At Epicell Skin Clinic in
Kymberley Dench
1 day ago4 min read
Anti Aging at Epicell Cosmetic Medicine Biostimulants Bioremodelling and Skin Health Treatments
Skin ageing is not only about lines. It is also about texture, tone, firmness, hydration, volume changes, and how well the skin repairs itself over time. That is why a modern cosmetic medicine plan should do more than chase a single wrinkle. At Epicell, the focus is on supporting skin health through evidence-informed treatments, careful assessment, and natural-looking results. Biostimulants, bioremodelling treatments, wrinkle-relaxing injections, skin boosters, and device-bas
Kymberley Dench
3 days ago7 min read
The Complete Guide to Broken Capillaries: Causes, Prevention & Effective Treatments
Broken capillaries, ook wel spider veins genoemd, zijn kleine zichtbare bloedvaatjes die vooral voorkomen op wangen, neus en kin. Ze ontstaan door factoren zoals genetische aanleg, zonbeschadiging, temperatuurschommelingen, alcoholgebruik, rosacea en huidveroudering. Hoewel ze onschuldig zijn, verdwijnen ze niet vanzelf en kunnen ze steeds zichtbaarder worden.
Peter Roodnat
3 days ago2 min read
Why Do I Look Tired Even When My Skin Looks Good?
Have you ever looked in the mirror and thought, “I look tired”, even when you've had a good night's sleep? You may have healthy skin, a good skincare routine and very few wrinkles, yet still feel that your face — particularly around the eyes — looks tired, heavy or less refreshed than it used to. The reason may not be your skin. As we age, changes occur in the skin, collagen, facial volume and the tissues surrounding the eyes. These changes can alter the way light and shadow
Kymberley Dench
10 hours ago5 min read
How and Why Does Our Face Age? Understanding Facial Ageing
Ageing is something every skin experiences, but facial ageing is much more complex than simply developing wrinkles. As we age, changes occur throughout the skin and the underlying structures of the face. Collagen and elastin gradually change, the skin can become thinner and less resilient, facial volume can shift or decrease, and changes occur within the deeper tissues that support the face. Environmental factors, particularly cumulative UV exposure, can accelerate some of th
Kymberley Dench
23 hours ago4 min read
Why Does Facial Redness Keep Coming Back? Causes, Triggers and Treatment
You may have noticed that your skin looks calmer after treatment, only for the redness to gradually return. This can be frustrating, particularly when you have invested time and money into improving your skin. The reason is that facial redness is often influenced by more than one factor. Some redness is associated with visible blood vessels, while other redness can be related to inflammation, rosacea, acne, sensitivity or environmental triggers. Understanding what is contribu
Kymberley Dench
23 hours ago4 min read
Rosacea or Broken Capillaries? Understanding the Cause of Red Skin
If you have red cheeks, a red nose or small visible blood vessels across your face, you may have wondered whether you have rosacea or simply broken capillaries. The two can look similar, and in some people they can occur together. Understanding the difference can help determine the most appropriate approach to managing your skin. At Epicell Skin Clinic in Pascoe Vale, Melbourne, we assess the skin carefully to determine whether redness appears to be associated with visible bl
Kymberley Dench
23 hours ago3 min read
Why Is My Face Always Red? Common Causes of Facial Redness
If your face frequently looks red, flushed or irritated, you may be wondering why it happens and whether it is simply sensitive skin or something that should be assessed. Facial redness is common and can have many different causes. For some people, redness comes and goes. For others, it becomes more persistent and may be associated with visible blood vessels, inflammation, rosacea, acne or sensitivity. At Epicell Skin Clinic in Pascoe Vale, Melbourne, we assess the skin caref
Kymberley Dench
23 hours ago4 min read
Why Does Pigmentation Come Back?
You've treated your pigmentation, your skin looks clearer, and then months later you notice those darker patches starting to appear again. Why does pigmentation come back? The answer is that pigmentation is often more than a surface problem. While a treatment may reduce the visible pigment, the factors that caused it can still be present. This is particularly relevant for conditions such as melasma, which can be persistent and prone to recurrence. At Epicell Skin Clinic in Pa
Kymberley Dench
1 day ago5 min read
Post-Inflammatory Pigmentation After Acne: Why It Happens and What Can Help
Your acne has finally settled, but you're still left with brown or darker marks where the breakouts were. If this sounds familiar, you may be experiencing post-inflammatory pigmentation after acne, also known as post-inflammatory hyperpigmentation or PIH. It is a common concern we see in clinic, and one of the most frustrating parts of having acne because the inflammation may have disappeared while the pigmentation remains. At Epicell Skin Clinic in Pascoe Vale, Melbourne, we
Kymberley Dench
1 day ago5 min read
Is It Pigmentation or Melasma? Understanding the Difference
If you have noticed brown or darker patches appearing on your face, you may have wondered: “Is this pigmentation or melasma?” Although the terms are sometimes used interchangeably, they are not the same thing. Pigmentation is a broad term used to describe areas of skin that appear darker than the surrounding skin. Melasma is a specific chronic pigmentary condition that can have different triggers and requires a more considered approach to treatment. At Epicell Skin Clinic in
Kymberley Dench
1 day ago4 min read
Anti Aging at Epicell Cosmetic Medicine Biostimulants Bioremodelling and Skin Health Treatments
Skin ageing is not only about lines. It is also about texture, tone, firmness, hydration, volume changes, and how well the skin repairs itself over time. That is why a modern cosmetic medicine plan should do more than chase a single wrinkle. At Epicell, the focus is on supporting skin health through evidence-informed treatments, careful assessment, and natural-looking results. Biostimulants, bioremodelling treatments, wrinkle-relaxing injections, skin boosters, and device-bas
Kymberley Dench
3 days ago7 min read
The Complete Guide to Broken Capillaries: Causes, Prevention & Effective Treatments
Broken capillaries, ook wel spider veins genoemd, zijn kleine zichtbare bloedvaatjes die vooral voorkomen op wangen, neus en kin. Ze ontstaan door factoren zoals genetische aanleg, zonbeschadiging, temperatuurschommelingen, alcoholgebruik, rosacea en huidveroudering. Hoewel ze onschuldig zijn, verdwijnen ze niet vanzelf en kunnen ze steeds zichtbaarder worden.
Peter Roodnat
3 days ago2 min read
Questions?
Rejuran, made from polynucleotides (PN) derived from salmon DNA, stimulates collagen production and repairs damaged skin for a smoother, more youthful appearance. For the face, it improves skin texture, reduces fine lines, and enhances hydration. Around the eyes, Rejuran strengthens the delicate skin, minimizing fine lines, dark circles, and crepiness for a refreshed look.
Yes, Rejuran can be used in conjunction with other treatments to enhance overall results. It pairs well with treatments like lasers, IPL, or RF microneedling to boost collagen production and accelerate skin healing. Additionally, combining Rejuran with volumising treatments or skin boosters can address both volume loss and skin quality, providing comprehensive rejuvenation.
Bio-stimulating products, work by stimulating the skin's natural collagen production to improve texture, elasticity, and firmness over time. Volumising products, provide immediate volume and contour to the face by physically filling areas of volume loss. While bio-stimulators have long-term effects by encouraging tissue regeneration, volumisers offer immediate but temporary results.
Acne Recommendation
Pigmentation
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